The highest governing body in Isabela State University is the Board of Regents. Its members are drawn from both the University and the private and public sectors. The current Board of Regents is composed of: 

	HON. SHIRLEY C. AGRUPIS, DPA CHAIRPERSON Commission on Higher Education
	HON. BOYET L. BAT ANG, Ph.D. VICE CHAIRPERSON President, Isabela State University
	HON. ALAN PETER S. CAYETANO Chair, Committee on Higher and Technical Education  Represented by: HON. MARIE ANJANETTE B. VICENTA Legislative Staff Officer
	HON.  MARK O. GO Chairperson, Committee on Higher and Technical Education Represented by: HON. ANTONIO T. ALBANO Representative, 1st Legislative District of lsabela
	HON. ROSE MARY G. AQUINO, Ph.D. Regional Executive Director, Department of Agriculture, R02
	HON. VIRGINIA G. BILGERA, DPA Regional Director, Department of Science and Technology, R02
	HON. DIONISIO C. LEDRES, JR. Regional Director, National Economic and Development Authority
	HON. RUBEN V. LOPEZ Private Sector Representative
	HON. JANIS RAE S. ESCAÑO Private Sector Representative
	HON. RAMON D. VELASCO, Ph.D. President, ISU Alumni Federation
	HON. LEX CEDRIC N. AQUINO President, Supreme Student Council Federation